Clincial Translation

Clinical Translation / Trials

Design, construction and testing of a low-cost automated 68Gallium-labeling synthesis unit

Am J Nucl Med Mol Imaging. 2016; 6(3): 176–184. The interest in 68Gallium labeled PET probes continues to increase around the world....

Comparison of the clinical performance of upper abdominal PET/DCE-MRI with and without MoCo

European Journal of Nuclear Medicine and Molecular Imaging. 2018 Nov;45(12):2147-2154. Purpose: To compare the clinical performance of...

18 F-Fluciclovine PET in Men With BCR PCa after Prostatectomy and planning for Salvage Radiation

Pract Radiat Oncol. Sep-Oct 2020;10(5):354-362 Purpose: Conventional imaging rarely localizes the site(s) of prostate cancer recurrence...

18 F-FES PET/CT Measurement of ER Suppression during a Phase I Trial of GDC-0810

Clin Cancer Res; 23(12); 3053-60. Purpose: Evaluate 18F-fluoroestradiol (FES) PET/CT as a biomarker of estrogen receptor (ER) occupancy...

C11 Methionine PET (MET-PET) Imaging of Glioblastoma for Detecting Postoperative Residual Disease

Int J Radiat Oncol Biol Phys. 2018 Nov 15; 102(4): 1024–1028. Purpose: Response criteria of glioblastoma after chemoradiation do not...

Clinical impact of PET/MR in treated colorectal cancer patients

European Journal of Nuclear Medicine and Molecular Imaging. 2019 Oct;46(11):2260-2269. Purpose: The primary aim of the present study was...

Management implications of FDG PET/MR in untreated intrahepatic cholangiocarcinoma

European Journal of Nuclear Medicine and Molecular Imaging. 2020 Jul;47(8):1871-1884. Purpose: Intrahepatic cholangiocarcinoma (ICC) is...

A Phase II Trial of Cabozantinib in Hormone Receptor-Positive Breast Cancer with Bone Metastases

Oncologist. 2020 Aug; 25(8): 652–660. Background We assessed the antitumor activity of cabozantinib, a potent multireceptor oral tyrosine...

Improving staging of rectal cancer in the pelvis: the role of PET/MRI

European Journal of Nuclear Medicine and Molecular Imaging. 2021 Apr;48(4):1235-1245. Purpose The role of positron emission...

PET/MRI assessment of lung nodules in primary abdominal malignancies: sensitivity and outcome analys

European Journal of Nuclear Medicine and Molecular Imaging. volume 48, pages 1976–1986 (2021) Purpose To evaluate PET/MR lung nodule...

Evaluation of the Diagnostic Performance of PET/MR for the Diagnosis of Liver Metastases

Invest Radiol. 2021 Mar 25. Objective: The aim of this study was to compare the performance of positron emission tomography...

The Impact of PET with 18F-Fluciclovine on the Treatment of BCR of PCa: Results from the LOCATE Tria

J Urol. 2019 Feb; 201(2): 322–331. Purpose: The prospective, multicenter LOCATE (F Fluciclovine [FACBC] PET/CT in Patients with Rising...

Multitargeted TKI produces discordant changes between 99mTc-MDP bone scans and other biomarkers

J Nucl Med. 2012 Nov; 53(11): 1670–1675. Purpose: One of the central unanswered questions in prostate cancer research is the significance...

Prospective trial with optical molecular imaging for percutaneous interventions in hepatic lesions

Radiology. 2015 Mar;274(3):917-26. Purpose: To demonstrate the clinical translation of optical molecular imaging (OMI) for the...

Pilot Clinical Trial of Indocyanine Green Fluorescence-Augmented Colonoscopy in High Risk Patients

Gastroenterol Res Pract. 2016; 2016: 6184842. White light colonoscopy is the current gold standard for early detection and treatment of...

Performance of fluciclovine PET/MR in the evaluation of osseous metastases from CRPC

Eur J Nucl Med Mol Imaging. 2020 Jan;47(1):105-114. Purpose: 18F-Fluciclovine is indicated for evaluation of suspected prostate cancer...

Impact of 18F-FDG PET/MR based tumor delineation in radiotherapy planning for cholangiocarcinoma

Abdom Radiol (NY). 2021 Mar 27. Purpose: Radiation therapy (RT) is an effective treatment for unresectable cholangiocarcinoma (CC)....

Baseline TLG measured with FDG PET/CT as a predictor of PFS in DLBCL

Am J Nucl Med Mol Imaging. 2013; 3(3): 272–281. This pilot study investigates the value of baseline total lesion glycolysis (TLG) in...

A phase one, single-dose, open-label, clinical safety and PET/MR imaging study of 68 Ga-DOTATOC

Am J Nucl Med Mol Imaging. 2017; 7(2): 53–62. This prospective pilot study provides a dynamic whole body PET/MR image database, clinical...